Article
Genetic Variation in Renal Expression of Folate Receptor 1 (Folr1) Gene Predisposes Spontaneously Hypertensive Rats to Metabolic Syndrome.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2016
Pravenec Michal, Kožich Viktor, Krijt Jakub, Sokolová Jitka, Zídek Václav, Landa Vladimír, Mlejnek Petr, Šilhavý Jan, Šimáková Miroslava, Škop Vojtěch, Trnovská Jaroslava, Kazdová Ludmila, Kajiya Takashi, Wang Jiaming, Kurtz Theodore W
Abstract excerpt
Metabolism of homocysteine and other sulfur amino acids is closely associated with metabolism of folates. In this study, we analyzed the possible role of folates and sulfur amino acids in the development of features of the metabolic syndrome in the BXH/HXB recombinant inbred strains derived from the spontaneously hypertensive rat (SHR) and Brown Norway progenitors. We mapped a quantitative trait locus for...
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