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Article

Renal cytochrome P4504A activity and salt sensitivity in spontaneously hypertensive rats.

Hypertension (Dallas, Tex. : 1979) - 1 Jun 1996

Stec D E, Trolliet M R, Krieger J E, Jacob H J, Roman R J

Abstract excerpt

Differences in the renal metabolism of arachidonic acid by cytochrome P450 have been reported in the spontaneously hypertensive rat (SHR) and Wistar-Kyoto rats, but the contribution of this system to the development of hypertension is unclear. The present study compared renal P450 activity and blood pressure in SHR and Brown-Norway rats (BN) under control conditions and in response to an elevation in sodium...

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Identifiers

PMID: 8641744
DOI: 10.1161/01.hyp.27.6.1329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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