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Article

Early alteration in glomerular reserve in humans at genetic risk of essential hypertension: mechanisms and consequences.

Hypertension (Dallas, Tex. : 1979) - 1 Mar 2001

O'Connor D T, Tyrell E A, Kailasam M T, Miller L M, Martinez J A, Henry R R, Parmer R J, Gabbai F B

Abstract excerpt

Essential hypertension has a familial predisposition, but the phenotype of elevated blood pressure has delayed penetrance. Because the kidney is a crucial determinant of blood pressure homeostasis, we studied early glomerular alterations in still-normotensive young subjects at genetic risk of hyp...

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Identifiers

PMID: 11244015
DOI: 10.1161/01.hyp.37.3.898

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11244015-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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