Article
Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats.
American journal of physiology. Renal physiology - 1 Dec 2007
Mattson David L, Dwinell Melinda R, Greene Andrew S, Kwitek Anne E, Roman Richard J, Cowley Allen W, Jacob Howard J
Abstract excerpt
This study examined the genetic basis for hypertension and renal disease phenotypes in Fawn Hooded hypertensive (FHH) rats using chromosome substitution strains (consomic rats) in which each of the 20 autosomes as well as the X and Y chromosomes were transferred from the normal Brown Norway (BN) rat onto the FHH genetic background. Male and female rats of each of the parental and consomic strains were maintained...
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