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Article

Isolation and confirmation of a calcium excretion quantitative trait locus on chromosome 1 in genetic hypercalciuric stone-forming congenic rats.

Journal of the American Society of Nephrology : JASN - 1 May 2006

Hoopes Richard R, Middleton Frank A, Sen Saunak, Hueber Paul A, Reid Robert, Bushinsky David A, Scheinman Steven J

Abstract excerpt

Hypercalciuria is the most common risk factor for kidney stones and has a substantial genetic component. The genetic hypercalciuric stone-forming (GHS) rat model displays complex changes in physiology involving intestine, bone, and kidney and overexpression of the vitamin D receptor, thereby repr...

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Identifiers

PMID: 16611718
DOI: 10.1681/ASN.2005080828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16611718-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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