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Article

[Mutations of epigenetic regulator genes and myeloid malignancies].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Nov 2015

Muto Tomoya, Sashida Goro, Oshima Motohiko, Iwama Atsushi

Abstract excerpt

Recent genome studies have identified recurrent somatic mutations in various myeloid malignancies, including acute myeloid leukemia, myelodysplastic syndrome and myeloproliferative neoplasm. These mutations frequently occur in epigenetic regulator genes, and functions of the proteins encoded by these genes in hematopoietic cells have been extensively analyzed, as reported recently. It is noteworthy that several...

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Share to DNA Methylation
Share to Epigenesis, Genetic
Share to ASXL1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to TET2 gene

Share to Leukemia, Myeloid

Share to Mutation

Share to Transcription, Genetic

Source

Identifiers

PMID: 26666714
DOI: 10.11406/rinketsu.56.2287

Genes

ASXL1
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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