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Epigenetics in the hematologic malignancies

1 Dec 2014

Abstract excerpt

A wealth of genomic and epigenomic data has identified abnormal regulation of epigenetic processes as a prominent theme in hematologic malignancies. Recurrent somatic alterations in myeloid malignancies of key proteins involved in DNA methylation, post-translational histone modification and chromatin remodeling have highlighted the importance of epigenetic regulation of gene expression in the initiation and...

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Share to Acute Myeloid Leukemia Research
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PMID: 25472952
DOI: 10.3324/haematol.2013.092007

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