Article
Recent Clinical Update of Acute Myeloid Leukemia: Focus on Epigenetic Therapies.
Journal of Korean medical science - 5 Apr 2021
Lee Eunyoung, Koh Youngil, Hong Junshik, Eom Hyeon Seok, Yoon Sung Soo
Abstract excerpt
Acute myeloid leukemia (AML) is a complicated disease characterized by genetic heterogeneity and simultaneous alterations in multiple genes. For decades, its only curative method has been intensive induction chemotherapy with or without allogeneic hematopoietic stem cell transplantation, and this approach cannot be applied to elderly patients, who make up more than 50% of AML patients. Recent advances in genomics...
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