Article
LRP5 associates with specific subsets of macrophages: Molecular and functional effects.
Journal of molecular and cellular cardiology - 1 Jan 2016
Borrell-Pages M, Romero J C, Crespo J, Juan-Babot O, Badimon L
Abstract excerpt
Innate and acquired immunity is involved in the progression of atherosclerosis. The molecular mechanisms ruling monocyte to macrophage (Mø) differentiation are not yet fully understood. Different subtypes of plaque macrophages that have differentiated from monocytes recruited from circulating blood, have been characterized based on surface epitopes. We have recently shown that LRP5, a member of the LDL receptor...
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