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Article

Soluble human leukocyte antigen G5 polarizes differentiation of macrophages toward a decidual macrophage-like phenotype.

Human reproduction (Oxford, England) - 1 Oct 2015

Lee Cheuk-Lun, Guo YiFan, So Kam-Hei, Vijayan Madhavi, Guo Yue, Wong Vera H H, Yao YuanQing, Lee Kai-Fai, Chiu Philip C N, Yeung William S B

Abstract excerpt

STUDY QUESTION: What are the actions of soluble human leukocyte antigen G5 (sHLAG5) on macrophage differentiation? SUMMARY ANSWER: sHLAG5 polarizes the differentiation of macrophages toward a decidual macrophage-like phenotype, which could regulate fetomaternal tolerance and placental development. WHAT IS KNOWN ALREADY: sHLAG5 is a full-length soluble isoform of human leukocyte antigen implicated in immune...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26307092
DOI: 10.1093/humrep/dev196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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