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Article

Activated Platelets Convert CD14+CD16- Into CD14+CD16+ Monocytes With Enhanced FcγR-Mediated Phagocytosis and Skewed M2 Polarization.

Frontiers in immunology - 1 Jan 2020

Lee Su Jeong, Yoon Bo Ruem, Kim Hee Young, Yoo Su-Jin, Kang Seong Wook, Lee Won-Woo

Abstract excerpt

Monocytes are important cellular effectors of innate immune defense. Human monocytes are heterogeneous and can be classified into three distinct subsets based on CD14 and CD16 expression. The expansion of intermediate CD14+CD16+ monocytes has been reported in chronic inflammatory diseases including rheumatoid arthritis (RA). However, the mechanism underlying induction of CD16 and its role in monocytes remains...

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Identifiers

PMID: 33488616
DOI: 10.3389/fimmu.2020.611133
PMCID: PMC7817612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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