Article
Native LDL promotes differentiation of human monocytes to macrophages with an inflammatory phenotype.
Thrombosis and haemostasis - 1 Apr 2016
Al-Sharea Annas, Lee Man Kit Sam, Moore Xiao-Lei, Fang Lu, Sviridov Dmitri, Chin-Dusting Jaye, Andrews Karen L, Murphy Andrew J
Abstract excerpt
Recruitment of monocytes in atherosclerosis is dependent upon increased levels of plasma lipoproteins which accumulate in the blood vessel wall. The extracellular milieu can influence the phenotype of monocyte subsets (classical: CD14++CD16-, intermediate: CD14+CD16+ and non-classical: CD14dimCD16++) and macrophages (M1 or M2) and consequently the initiation, progression and/or regression of atherosclerosis....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.