Article
Monocyte subsets in human liver disease show distinct phenotypic and functional characteristics.
Hepatology (Baltimore, Md.) - 1 Jan 2013
Liaskou Evaggelia, Zimmermann Henning W, Li Ka-Kit, Oo Ye H, Suresh Shankar, Stamataki Zania, Qureshi Omar, Lalor Patricia F, Shaw Jean, Syn Wing-kin, Curbishley Stuart M, Adams David H
Abstract excerpt
UNLABELLED: Liver fibrosis is a wound healing response to chronic liver injury and inflammation in which macrophages and infiltrating monocytes participate in both the development and resolution phase. In humans, three monocyte subsets have been identified: the classical CD14++CD16-, intermediate CD14++CD16+, and nonclassical CD14+CD16++ monocytes. We studied the phenotype and function of these monocyte subsets...
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