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Article

Inhibition of hepatitis B virus (HBV) gene expression and replication by HBx gene silencing in a hydrodynamic injection mouse model with a new clone of HBV genotype B.

Virology journal - 28 Jun 2013

Li Lei, Shen Hong, Li Anyi, Zhang Zhenhua, Wang Baoju, Wang Junzhong, Zheng Xin, Wu Jun, Yang Dongliang, Lu Mengji, Song Jingjiao

Abstract excerpt

BACKGROUND: It has been suggested that different hepatitis B virus (HBV) genotypes may have distinct virological characteristics that correlate with clinical outcomes during antiviral therapy and the natural course of infection. Hydrodynamic injection (HI) of HBV in the mouse model is a useful tool for study of HBV replication in vivo. However, only HBV genotype A has been used for studies with HI. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23805945
DOI: 10.1186/1743-422X-10-214
PMCID: PMC3751867

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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