Article
Early dynamics of hepatitis B virus in chimeric mice carrying human hepatocytes monoinfected or coinfected with genotype G.
Hepatology (Baltimore, Md.) - 1 Apr 2007
Sugiyama Masaya, Tanaka Yasuhito, Sakamoto Tomoyuki, Maruyama Isao, Shimada Takashi, Takahashi Satoru, Shirai Tomoyuki, Kato Hideaki, Nagao Masataka, Miyakawa Yuzo, Mizokami Masashi
Abstract excerpt
UNLABELLED: Of the 8 genotypes of HBV (genotypes A-H), genotype G is unique in that it has an insertion in the core gene and two stop codons in the precore region preventing the synthesis of hepatitis B e antigen. Most individuals with genotype G are coinfected with other genotypes, typically genotype A. Mice with severe combined immunodeficiency disease carrying human hepatocytes were infected with HBV particles...
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