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Influence of hepatitis B virus genotypes on the intra- and extracellular expression of viral DNA and antigens.

Hepatology (Baltimore, Md.) - 1 Oct 2006

Sugiyama Masaya, Tanaka Yasuhito, Kato Takanobu, Orito Etsuro, Ito Kiyoaki, Acharya Subrat K, Gish Robert G, Kramvis Anna, Shimada Takashi, Izumi Namiki, Kaito Masahiko, Miyakawa Yuzo, Mizokami Masashi

Abstract excerpt

Various genotypes of the hepatitis B virus (HBV) induce liver disease of distinct severity, but the underlying virological differences are not well defined. Huh7 cells were transfected with plasmids carrying 1.24-fold the HBV genome of different genotypes/subgenotypes (2 strains each for Aa/A1, Ae/A2, Ba/B2 and D; 3 each for Bj/B1 and C). HBV DNA levels in cell lysates, determined by Southern hybridization, were...

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Identifiers

PMID: 17006908
DOI: 10.1002/hep.21345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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