Article
Genome-wide linkage on chromosome 10q26 for a dimensional scale of major depression.
Journal of affective disorders - 1 Feb 2016
Knowles Emma E M, Kent Jack W, McKay D Reese, Sprooten Emma, Mathias Samuel R, Curran Joanne E, Carless Melanie A, de Almeida Marcio A A, Harald H H Goring, Dyer Tom D, Olvera Rene L, Fox Peter T, Duggirala Ravi, Almasy Laura, Blangero John, Glahn David C
Abstract excerpt
Major depressive disorder (MDD) is a common and potentially life-threatening mood disorder. Identifying genetic markers for depression might provide reliable indicators of depression risk, which would, in turn, substantially improve detection, enabling earlier and more effective treatment. The aim of this study was to identify rare variants for depression, modeled as a continuous trait, using linkage and post-hoc...
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