Article
The genetic basis of major depression.
Psychological medicine - 1 Oct 2021
Kendall K M, Van Assche E, Andlauer T F M, Choi K W, Luykx J J, Schulte E C, Lu Y
Abstract excerpt
Major depressive disorder (MDD) is a common, debilitating, phenotypically heterogeneous disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders, its high prevalence, moderate heritability, and strong polygenicity have posed major challenges for gene-mapping in MDD. Studies of common genetic variation in MDD, driven by large international collaborations such as the Psychiatric...
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