Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent.

Nature genetics - 1 Sept 2016

Hyde Craig L, Nagle Michael W, Tian Chao, Chen Xing, Paciga Sara A, Wendland Jens R, Tung Joyce Y, Hinds David A, Perlis Roy H, Winslow Ashley R

Abstract excerpt

Despite strong evidence supporting the heritability of major depressive disorder (MDD), previous genome-wide studies were unable to identify risk loci among individuals of European descent. We used self-report data from 75,607 individuals reporting clinical diagnosis of depression and 231,747 individuals reporting no history of depression through 23andMe and carried out meta-analysis of these results with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Genome-Wide Association Study

Share to Meta-Analysis as Topic

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 27479909
DOI: 10.1038/ng.3623
PMCID: PMC5706769

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent.PMID 27479909Read ↗

The successful search for genetic loci associated with depression.Semantic proximity Read ↗

The genetic basis of major depression.Semantic proximity Read ↗

Genetics of Depression: Progress at Last.Semantic proximity Read ↗

Exome-wide screening identifies novel rare risk variants for major depression disorder.Semantic proximity Read ↗

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.Semantic proximity Read ↗

Overview of the genetics of major depressive disorder.Semantic proximity Read ↗

The genetics of major depression.Semantic proximity Read ↗

The Australian Genetics of Depression Study: New Risk Loci and Dissecting Heterogeneity Between Subtypes.Semantic proximity Read ↗

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.Semantic proximity Read ↗

Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.Semantic proximity Read ↗

The Role of Genetic Data in Dissecting Depression Heterogeneity.Semantic proximity Read ↗

A genome-wide association study of depressive symptoms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.