Article

Whole genome linkage analysis in a large Brazilian multigenerational family reveals distinct linkage signals for Bipolar Disorder and Depression

2017-02-06

Abstract excerpt

Both common and rare genetic variation play a role in the causes for mood disorders. Very large families pose unique opportunities and analytical challenges but may provide a way to identify regions and mutations associated with mood disorders. We identified a family with a high prevalence (~30%) of mood disorders in a rural village in Brazil, featuring decreasing age of onset over generations. The pattern of inhe...

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Literature Corpus work: 60199e0e-bdba-5aed-a55f-0201b0aac664
DOI: 10.1101/106260

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