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Article

Regulatory single nucleotide polymorphisms at the beginning of intron 2 of the human KRAS gene.

Journal of biosciences - 1 Dec 2015

Antontseva Elena V, Matveeva Marina Yu, Bondar Natalia P, Kashina Elena V, Leberfarb Elena Yu, Bryzgalov Leonid O, Gervas Polina A, Ponomareva Anastasia A, Cherdyntseva Nadezhda V, Orlov Yury L, Merkulova Tatiana I

Abstract excerpt

There are two regulatory single nucleotide polymorphisms (rSNPs) at the beginning of the second intron of the mouse K-ras gene that are strongly associated with lung cancer susceptibility. We performed functional analysis of three SNPs (rs12228277: T greater than A, rs12226937: G greater than A, and rs61761074: T greater than G) located in the same region of human KRAS. We found that rs12228277 and rs61761074...

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Source

Identifiers

PMID: 26648033
DOI: 10.1007/s12038-015-9567-8

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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