Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Extensive sequence variation in the 3' untranslated region of the KRAS gene in lung and ovarian cancer cases.

Cell cycle (Georgetown, Tex.) - 1 Jan 2014

Kim Minlee, Chen Xiaowei, Chin Lena J, Paranjape Trupti, Speed William C, Kidd Kenneth K, Zhao Hongyu, Weidhaas Joanne B, Slack Frank J

Abstract excerpt

While cancer is a serious health issue, there are very few genetic biomarkers that predict predisposition, prognosis, diagnosis, and treatment response. Recently, sequence variations that disrupt microRNA (miRNA)-mediated regulation of genes have been shown to be associated with many human diseases, including cancer. In an early example, a variant at one particular single nucleotide polymorphism (SNP) in a let-7...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Carcinoma, Ovarian Epithelial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MicroRNAs

Share to Neoplasms, Glandular and Epithelial

Share to Ovarian Neoplasms

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24552817
DOI: 10.4161/cc.27941
PMCID: PMC3984301

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Extensive sequence variation in the 3' untranslated region of the KRAS gene in lung and ovarian cancer cases.PMID 24552817Read ↗

KRAS alleles: the LCS6 3'UTR variant and KRAS coding sequence mutations in the NCI-60 panel.Semantic proximity Read ↗

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk.Semantic proximity Read ↗

A variant in 3'-untranslated region of KRAS compromises its interaction with hsa-let-7g and contributes to the development of lung cancer in patients with COPD.Semantic proximity Read ↗

Transcriptome-wide analysis of UTRs in non-small cell lung cancer reveals cancer-related genes with SNV-induced changes on RNA secondary structure and miRNA target sites.Semantic proximity Read ↗

A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk.Semantic proximity Read ↗

Human cell line model for cancer-associated KRAS noncoding SNP.Semantic proximity Read ↗

Prevalence of the variant allele rs61764370 T>G in the 3'UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer families.Semantic proximity Read ↗

Association of Rs61764370 polymorphism within let-7 microRNA-binding site with lung cancer in Iranian population.Semantic proximity Read ↗

MicroRNA-mediated regulation of KRAS in cancer.Semantic proximity Read ↗

KRAS SNPs are related to colorectal cancer susceptibility and survival in Chinese people.Semantic proximity Read ↗

Association of rs712 polymorphism in Kras gene 3'-luntranslated region and cancer risk: a meta-analysis.Semantic proximity Read ↗

rs61764370 polymorphism of Kras and risk of cancer in Caucasian population: A meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.