Article
Lack of association between let-7 binding site polymorphism rs712 and risk of nasopharyngeal carcinoma.
Familial cancer - 1 Mar 2014
Pan Xin-Min, Jia Jing, Guo Xiao-Min, Li Zhao-Hui, Zhang Zhen, Qin Hao-Jie, Xu Guo-Hui, Gao Lin-Bo
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is characterized by its highly invasive and metastatic features. Therefore, screening genetic biomarkers of NPC to achieve early diagnose would be of great value for NPC therapy. Single nucleotide polymorphisms in let-7 miRNA binding site in 3' untranslated region of KRAS mRNA have been found to be associated with various cancer risks. In this study, we genotyped the frequency of...
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