Article
Serotonin Transporter (SLC6A4) and FK506-Binding Protein 5 (FKBP5) Genotype and Methylation Relationships with Response to Meditation in Veterans with PTSD.
Molecular neurobiology - 1 Nov 2024
Lee Adam, Thuras Paul, Baller Joshua, Jiao Chuan, Guo Bin, Erbes Christopher R, Polusny Melissa A, Liu Chunyu, Wu Baolin, Lim Kelvin O, Bishop Jeffrey R
Abstract excerpt
Meditation-based interventions are novel and effective non-pharmacologic treatments for veterans with PTSD. We examined relationships between treatment response, early life trauma exposure, DNA polymorphisms, and methylation in the serotonin transporter (SLC6A4) and FK506-binding protein 5 (FKBP5) genes. DNA samples and clinical outcomes were examined in 72 veterans with PTSD who received meditation-based therapy...
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