Article
Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk.
Oncotarget - 15 Dec 2015
Walsh Kyle M, Codd Veryan, Rice Terri, Nelson Christopher P, Smirnov Ivan V, McCoy Lucie S, Hansen Helen M, Elhauge Edward, Ojha Juhi, Francis Stephen S, Madsen Nils R, Bracci Paige M, Pico Alexander R, Molinaro Annette M, Tihan Tarik, Berger Mitchel S, Chang Susan M, Prados Michael D, Jenkins Robert B, Wiemels Joseph L, Samani Nilesh J, Wiencke John K, Wrensch Margaret R
Abstract excerpt
Telomere maintenance has emerged as an important molecular feature with impacts on adult glioma susceptibility and prognosis. Whether longer or shorter leukocyte telomere length (LTL) is associated with glioma risk remains elusive and is often confounded by the effects of age and patient treatment. We sought to determine if genotypically-estimated LTL is associated with glioma risk and if inherited single...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.