Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relationship between genetically determined telomere length and glioma risk.

Neuro-oncology - 1 Feb 2022

Saunders Charlie N, Kinnersley Ben, Culliford Richard, Cornish Alex J, Law Philip J, Houlston Richard S

Abstract excerpt

BACKGROUND: Telomere maintenance is increasingly recognized as being fundamental to glioma oncogenesis with longer leukocyte telomere length (LTL) reported to increase risk of glioma. To gain further insight into the relationship between telomere genetics and risk of glioma, we conducted several complementary analyses, using genome-wide association studies data on LTL (78 592 individuals) and glioma (12 488 cases...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome-Wide Association Study
Share to Glioma
Share to Leukocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Telomere

Share to Telomere Homeostasis

Source

Open in PubMed Open full text

Identifiers

PMID: 34477880
DOI: 10.1093/neuonc/noab208
PMCID: PMC8804896

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relationship between genetically determined telomere length and glioma risk.PMID 34477880Read ↗

Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk.Semantic proximity Read ↗

Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.Semantic proximity Read ↗

Telomere maintenance and the etiology of adult gliomaSemantic proximity Read ↗

Relationship between genetically determined telomere length and childhood glioma risk.Semantic proximity Read ↗

Searching for causal relationships of glioma: a phenome-wide Mendelian randomisation study.Semantic proximity Read ↗

Association between leukocyte telomere length and glioma risk: a case-control studySemantic proximity Read ↗

Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis.Semantic proximity Read ↗

1p34.2 rs621559 and 14q21 rs398652 leukocyte telomere length-related genetic variants contribute to glioma susceptibility.Semantic proximity Read ↗

Genetics in glioma: lessons learned from genome-wide association studies.Semantic proximity Read ↗

Leukocyte telomere length: a novel biomarker to predict the prognosis of glioma patientsSemantic proximity Read ↗

Assessing the Relationship Between Leukocyte Telomere Length and Cancer Risk/Mortality in UK Biobank and TCGA Datasets With the Genetic Risk Score and Mendelian Randomization ApproachesSemantic proximity Read ↗

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.