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Article

Determinants of frequency-dependent regulation of Kv1.2-containing potassium channels.

Channels (Austin, Tex.) - 1 Jan 2016

Baronas Victoria A, Yang Runying, Vilin Yury Y, Kurata Harley T

Abstract excerpt

Voltage-gated potassium channels are important regulators of electrical excitation in many tissues, with Kv1.2 standing out as an essential contributor in the CNS. Genetic deletion of Kv1.2 invariably leads to early lethality in mice. In humans, mutations affecting Kv1.2 function are linked to epileptic encephalopathy and movement disorders. We have demonstrated that Kv1.2 is subject to a unique regulatory...

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Identifiers

PMID: 26646078
DOI: 10.1080/19336950.2015.1120390
PMCID: PMC4960988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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