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Article

Extracellular redox sensitivity of Kv1.2 potassium channels.

Scientific reports - 22 Aug 2017

Baronas Victoria A, Yang Runying Y, Kurata Harley T

Abstract excerpt

Kv1.2 is a prominent potassium channel subtype in the nervous system and serves as an important structural template for investigation of ion channel function. However, Kv1.2 voltage-dependence exhibits dramatic cell-to-cell variability due to a gating mode shift that is regulated by an unknown mechanism. We report that this variable behavior is regulated by the extracellular redox environment. Exposure to...

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Identifiers

PMID: 28831076
DOI: 10.1038/s41598-017-08718-z
PMCID: PMC5567313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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