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Article

Protein kinase a mediates activity-dependent Kv4.2 channel trafficking.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 23 Jul 2008

Hammond Rebecca S, Lin Lin, Sidorov Michael S, Wikenheiser Andrew M, Hoffman Dax A

Abstract excerpt

The A-type potassium channel subunit Kv4.2 influences hippocampal function through regulation of dendritic excitability, and changes in Kv4.2 surface expression alter synaptic plasticity. Recent data from our laboratory demonstrate that EGFP (enhanced green fluorescent protein)-tagged Kv4.2 channels located in dendritic spines are internalized in an activity-dependent manner after synaptic stimulation and during...

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Identifiers

PMID: 18650329
DOI: 10.1523/JNEUROSCI.1951-08.2008
PMCID: PMC2665045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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