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Article

Antigenic Determinants of the Bilobal Cockroach Allergen Bla g 2.

The Journal of biological chemistry - 29 Jan 2016

Woodfolk Judith A, Glesner Jill, Wright Paul W, Kepley Christopher L, Li Mi, Himly Martin, Muehling Lyndsey M, Gustchina Alla, Wlodawer Alexander, Chapman Martin D, Pomés Anna

Abstract excerpt

Bla g 2 is a major indoor cockroach allergen associated with the development of asthma. Antigenic determinants on Bla g 2 were analyzed by mutagenesis based on the structure of the allergen alone and in complex with monoclonal antibodies that interfere with IgE antibody binding. The structural analysis revealed mechanisms of allergen-antibody recognition through cation-π interactions. Single and multiple Bla g 2...

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Identifiers

PMID: 26644466
DOI: 10.1074/jbc.M115.702324
PMCID: PMC4732212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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