Article
Designing hypoallergenic derivatives for allergy treatment by means of in silico mutation and screening.
The Journal of allergy and clinical immunology - 1 Apr 2010
Thalhamer Theresa, Dobias Heidi, Stepanoska Tatjana, Pröll Martina, Stutz Hanno, Dissertori Oliver, Lackner Peter, Ferreira Fatima, Wallner Michael, Thalhamer Josef, Hartl Arnulf
Abstract excerpt
BACKGROUND: The incidence of allergic diseases in developed countries has been increasing constantly in the last 2 decades. The only curative treatment available thus far is specific immunotherapy (SIT). The problematic side effects that can occur during SIT with allergen extracts led to the search for safer alternatives, such as recombinant hypoallergenic proteins with reduced allergenic potential and preserved...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.