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Article

Characterization of an anti-Bla g 1 scFv: epitope mapping and cross-reactivity.

Molecular immunology - 1 Jun 2014

Mueller Geoffrey A, Ankney John A, Glesner Jill, Khurana Taruna, Edwards Lori L, Pedersen Lars C, Perera Lalith, Slater Jay E, Pomés Anna, London Robert E

Abstract excerpt

Bla g 1 is a major allergen from Blatella germanica and one of the primary allergens used to assess cockroach allergen exposure. The epitope of an anti-Bla g 1 scFv was mapped in order to better understand cross reactivity with other group 1 cockroach allergens and patient IgE epitopes. X-ray crystallography was used to determine the structure of the scFv. The scFv epitope on Bla g 1 was located by alanine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24667070
DOI: 10.1016/j.molimm.2014.02.003
PMCID: PMC4097036

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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