Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigation of Potentially Deleterious Alleles for Response to Cancer Treatment with 5-Fluorouracil.

Anticancer research - 1 Dec 2015

Cavalcante Giovanna Chaves, Freitas Natalle Do Socorro Da Costa, Ribeiro-Dos-Santos André Maurício, De Carvalho Darlen Cardoso, Da Silva Ellen Moreno, De Assumpção Paulo Pimentel, Ribeiro-Dos-Santos Ândrea, Santos Sidney, Dos Santos Ney Pereira Carneiro

Abstract excerpt

AIM: To investigate polymorphisms that are probable indicators of response variability during cancer treatment with 5-fluorouracil (rs16430, rs2279198, rs1801159 and rs17878362). MATERIALS AND METHODS: We investigated 1,038 individuals regarding allele distribution from different populations, out of which we genotyped 127 individuals from a Brazilian admixed population. Similarity analyses with parental...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Black People
Share to Brazil
Share to Dihydrouracil Dehydrogenase (NADP)
Share to Fluorouracil
Share to Multienzyme Complexes
Share to Orotidine-5'-Phosphate Decarboxylase
Share to Thymidylate Synthase

Source

Identifiers

PMID: 26637924

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigation of Potentially Deleterious Alleles for Response to Cancer Treatment with 5-Fluorouracil.PMID 26637924Read ↗

Genetic variants influencing fluoropyrimidine based-therapy and available methods to detect them.Semantic proximity Read ↗

Pharmacogenomics in colorectal cancer: a genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration.Semantic proximity Read ↗

Involvement of target gene polymorphisms in 5-Fluorouracil toxicity: a case report.Semantic proximity Read ↗

Prediction of severe toxicity in adult patients under treatment with 5-fluorouracil: a prospective cohort study.Semantic proximity Read ↗

Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05.Semantic proximity Read ↗

Use of a Comprehensive Panel of Biomarkers to Predict Response to a Fluorouracil–Oxaliplatin Regimen in Patients with Metastatic Colorectal CancerSemantic proximity Read ↗

Expression quantitative trait loci in ABC transporters are associated with survival in 5-FU treated colorectal cancer patients.Semantic proximity Read ↗

Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and FOLFOX response in colorectal cancer patientsSemantic proximity Read ↗

Combination of germline variations associated with survival of folinic acid, fluorouracil and irinotecan-treated metastatic colorectal cancer patients.Semantic proximity Read ↗

Concordance of genotype for polymorphisms in DNA isolated from peripheral blood and colorectal cancer tumor samples.Semantic proximity Read ↗

Translational medicine and reliability of single-nucleotide polymorphism studies: can we believe in SNP reports or not?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.