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Article

Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Apr 2007

Ruzzo Annamaria, Graziano Francesco, Loupakis Fotios, Rulli Eliana, Canestrari Emanuele, Santini Daniele, Catalano Vincenzo, Ficarelli Rita, Maltese Paolo, Bisonni Renato, Masi Gianluca, Schiavon Gaia, Giordani Paolo, Giustini Lucio, Falcone Alfredo, Tonini Giuseppe, Silva Rosarita, Mattioli Rodolfo, Floriani Irene, Magnani Mauro

Abstract excerpt

PURPOSE: The objective is to investigate whether polymorphisms with putative influence on fluorouracil/oxaliplatin activity are associated with clinical outcomes of patients with advanced colorectal cancer treated with first-line oxaliplatin, folinic acid, and fluorouracil palliative chemotherapy...

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Source

Identifiers

PMID: 17401013
DOI: 10.1200/JCO.2006.08.1844

Genes

GSTP1
ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17401013-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy.PMID 17401013Read ↗

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