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Article

Concordance of genotype for polymorphisms in DNA isolated from peripheral blood and colorectal cancer tumor samples.

Pharmacogenomics - 1 Dec 2013

van Huis-Tanja Lieke, Kweekel Dinemarie, Gelderblom Hans, Koopman Miriam, Punt Kees, Guchelaar Henk-Jan, van der Straaten Tahar

Abstract excerpt

BACKGROUND & AIM: Results from different pharmacogenetic association studies in colorectal cancer are often conflicting. Both peripheral blood and formalin-fixed, paraffin-embedded (FFPE) tissue are routinely used as DNA source. This could cause bias due to somatic alterations in tumor tissue, such as loss of heterozygosity. We therefore compared genotypes in DNA from peripheral blood and FFPE colorectal tumor...

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Identifiers

PMID: 24279855
DOI: 10.2217/pgs.13.169

Genes

GSTP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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