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Article

The ESR2 AluI gene polymorphism is associated with bone mineral density in postmenopausal women.

The Journal of steroid biochemistry and molecular biology - 1 Nov 2011

Currò Monica, Marini Herbert, Alibrandi Angela, Ferlazzo Nadia, Condello Salvatore, Polito Francesca, Adamo Elena B, Atteritano Marco, D'Anna Rosario, Altavilla Domenica, Bitto Alessandra, Squadrito Francesco, Ientile Riccardo, Caccamo Daniela

Abstract excerpt

Multiple factors may contribute to the pathogenesis of postmenopausal osteoporosis including environmental, life-style and genetic factors. Common variants in ESR2 gene encoding for ER-beta, highly expressed in bone tissue, have recently been proposed as candidates for affecting bone phenotype at the population level, particularly in postmenopausal women. In this study, we examined the genetic background at ESR2...

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Identifiers

PMID: 21689747
DOI: 10.1016/j.jsbmb.2011.05.008

Genes

ESR2

Variants

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