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Association of plasma level of high-mobility group box-1 with necroptosis and sepsis outcomes

4 May 2021

Abstract excerpt

Abstract The role of high-mobility group box-1 (HMGB1) in outcome prediction in sepsis is controversial. Furthermore, its association with necroptosis, a programmed cell necrosis mechanism, is still unclear. The purpose of this study is to identify the association between the plasma levels of HMGB1 and the severity and clinical outcomes of sepsis, and to examine the correlation between HMGB1 and key executors of...

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PMID: 33947887
DOI: 10.1038/s41598-021-88970-6

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