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Article

Genetic polymorphisms in sepsis and septic shock: role in prognosis and potential for therapy.

Chest - 1 Sept 2003

Holmes Cheryl L, Russell James A, Walley Keith R

Abstract excerpt

Genetic epidemiologic studies suggest a strong genetic influence on the outcome from sepsis, and genetics may explain the wide variation in the individual response to infection that has long puzzled clinicians. Several candidate genes have been identified as important in the inflammatory response and investigated in case-controlled studies, including the tumor necrosis factor (TNF)-alpha and TNF-beta genes,...

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PMID: 12970043
DOI: 10.1378/chest.124.3.1103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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