Article
IL-1B rs16944 polymorphism is related to septic shock and death.
European journal of clinical investigation - 1 Jan 2017
Jiménez-Sousa María Ángeles, Medrano Luz M, Liu Pilar, Almansa Raquel, Fernández-Rodríguez Amanda, Gómez-Sánchez Esther, Rico Lucía, Heredia-Rodríguez María, Gómez-Pesquera Estefanía, Tamayo Eduardo, Resino Salvador
Abstract excerpt
BACKGROUND: IL-1β is a primary mediator of systemic inflammatory response syndrome (SIRS) and it may lead to shock septic. Our aim was to analyse whether IL-1B rs16944 polymorphism is associated with the onset of septic shock and death after major surgery. MATERIALS AND METHODS: We performed a case-control study on 467 patients who underwent major cardiac or abdominal surgery. Of them, 205 patients developed...
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