Article
Association study of MCP-1 promoter polymorphisms with the susceptibility and progression of sepsis.
PloS one - 1 Jan 2017
He Junbing, Chen Yuhua, Lin Yao, Zhang Wenying, Cai Yujie, Chen Feng, Liao Qinghui, Yin Zihan, Wang Yan, Tao Shoubao, Lin Xiaoli, Huang Pengru, Cui Lili, Shao Yiming
Abstract excerpt
Previous studies have indicated that the monocyte chemo-attractant protein 1 (MCP-1), also referred to as C-C motif chemokine ligand 2 (CCL2), plays a significant role in the pathogenesis of sepsis, and this study investigated the clinical relevance of two MCP-1 gene polymorphisms on sepsis onset and progression. The Multiplex SNaPshot genotyping method was used to detect MCP-1 gene polymorphisms in the Chinese...
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