Article
Genome-wide haplotype association study identify TNFRSF1A, CASP7, LRP1B, CDH1 and TG genes associated with Alzheimer's disease in Caribbean Hispanic individuals.
Oncotarget - 15 Dec 2015
Shang Zhenwei, Lv Hongchao, Zhang Mingming, Duan Lian, Wang Situo, Li Jin, Liu Guiyou, Ruijie Zhang, Jiang Yongshuai
Abstract excerpt
Alzheimer's disease (AD) is an acquired disorder of cognitive and behavioral impairment. It is considered to be caused by variety of factors, such as age, environment and genetic factors. In order to identify the genetic affect factors of AD, we carried out a bioinformatic approach which combined genome-wide haplotype-based association study with gene prioritization. The raw SNP genotypes data was downloaded from...
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