Article

Multi-omics Characterization of Epigenetic and Genetic Risk of Alzheimer Disease in Autopsied Brains from two Ethnic Groups

2024-02-14

Abstract excerpt

<h4>Background</h4> Both genetic variants and epigenetic features contribute to the risk of Alzheimer’s disease (AD). We studied the AD association of CpG-related single nucleotide polymorphisms (CGS), which act as the hub of both the genetic and epigenetic effects, in Hispanics decedents and generalized the findings to Non-Hispanic Whites (NHW) decedents. <h4>Methods</h4> First, we derived the dosage of the CpG s...

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Literature Corpus work: 416c883f-63ac-5702-8ba6-7c97e94655ca
DOI: 10.1101/2024.02.12.24302533

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