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Article

Association of Genetic Variants of the Interleukin-17F rs763780 and its Circulating Level in Psoriasis Patients in Egypt.

The Egyptian journal of immunology - 1 Jun 2020

Fouad Nehad A, Akl Essam M, Ahmed Shereen H

Abstract excerpt

Psoriasis is a chronic autoimmune disease affecting the skin and joints, IL- 17 family has been shown to be the major effector cytokine in its pathogenesis. This study aimed to investigate genetic polymorphism of IL-17F (rs763780) and evaluate the impact of this polymorphism on circulating levels of IL-17F as a potential risk locus for psoriasis. 60 patients suffering from chronic plaque psoriasis and 60 healthy...

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PMID: 33548976

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