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Article

Absence of association of interleukin-18 gene polymorphisms with primary immune thrombocytopenia in a Chinese Han population.

DNA and cell biology - 1 Aug 2014

Li Huiyuan, Xuan Min, Xue Feng, Liu Xiaofan, Zhang Donglei, Fu Rongfeng, Yang Yanhui, Zhang Xian, Yang Renchi

Abstract excerpt

Interleukin-18 (IL-18) is an inflammatory cytokine that plays an important role in autoimmune disease by inducing interferon-γ secretion. Considering the abnormal serum concentration of IL-18 in primary immune thrombocytopenia (ITP) patients and the regulated effect of IL-18 gene polymorphisms on its production, the aim of this study was to investigate a possible association between the IL-18 promoter...

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Identifiers

PMID: 24742099
DOI: 10.1089/dna.2013.2247
PMCID: PMC4117256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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