Article
Association of IL-17F rs763780 polymorphism and risk of psoriasis in Turkish population: a case-control study.
Anais brasileiros de dermatologia - 1 Jan 2000
Akadam-Teker Ayşegül Başak, Akşan Burak
Abstract excerpt
BACKGROUND: Psoriasis represents a chronic inflammatory phenotype shaped by genetic interactions, characterized by keratinocyte hyperproliferation and commonly affecting the skin and joints. Experimental and clinical studies suggest that the IL-17F gene locus plays a role as a central cytokine in the immunopathogenesis of psoriasis. OBJECTIVES: Based on the central role of IL-17F in the pathogenesis of psoriasis,...
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