Article
Interleukin-17A and -17F single nucleotide polymorphisms associate with susceptibility of asthma in Chinese Han population.
Human immunology - 1 Oct 2018
Liang Tao, Xu Yi Ting, Zhang Yang, Cai Peng Cheng, Hu Li Hua
Abstract excerpt
Interleukin 17 (IL-17) plays important roles in the progression of asthma. Genetic variants in the Il-17 may influence the immunopathogenesis of many diseases. Many studies have investigated the relevance of IL-17 polymorphism with cancers or immune diseases, including asthma. In this study, single nucleotide polymorphisms (SNPs) of IL-17 were explored by PCR-RFLP and verified by sequencing method. The...
Topics
- Adult
- Alleles
- Asian People
- Asthma
- Case-Control Studies
- China
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Immunoglobulin E
