Article
HiC-Pro: an optimized and flexible pipeline for Hi-C data processing.
Genome biology - 1 Dec 2015
Servant Nicolas, Varoquaux Nelle, Lajoie Bryan R, Viara Eric, Chen Chong-Jian, Vert Jean-Philippe, Heard Edith, Dekker Job, Barillot Emmanuel
Abstract excerpt
HiC-Pro is an optimized and flexible pipeline for processing Hi-C data from raw reads to normalized contact maps. HiC-Pro maps reads, detects valid ligation products, performs quality controls and generates intra- and inter-chromosomal contact maps. It includes a fast implementation of the iterative correction method and is based on a memory-efficient data format for Hi-C contact maps. In addition, HiC-Pro can...
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