Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex determination in the germ line of Drosophila melanogaster: activation of the gene Sex-lethal.

Development (Cambridge, England) - 1 Jul 1993

Granadino B, Santamaria P, Sánchez L

Abstract excerpt

The germ line exhibits sexual dimorphism as do the somatic tissues. Cells with the 2X;2A chromosome constitution will follow the oogenic pathway and X;2A cells will develop into sperm. In both somatic and germ-line tissues, the sexual pathway chosen by the cells depends on the gene Sex-lethal (Sxl), whose function is continuously needed for female development. In the soma, the sex of the cells is autonomously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to Drosophila melanogaster
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Mutation

Share to Nuclear Proteins

Share to Transcription Factors

Share to X Chromosome

Source

Identifiers

PMID: 8076519
DOI: 10.1242/dev.118.3.813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex determination in the germ line of Drosophila melanogaster: activation of the gene Sex-lethal.PMID 8076519Read ↗

Sex determination in Drosophila: sis-b, a major numerator element of the X:A ratio in the soma, does not contribute to the X:A ratio in the germ line.Semantic proximity Read ↗

<i>sisterless A</i> is required for activation of <i>Sex lethal</i> in the <i>Drosophila</i> germlineSemantic proximity Read ↗

Drosophila melanogaster male somatic cells feminized solely by TraF can collaborate with female germ cells to make functional eggs.Semantic proximity Read ↗

Sex determination of germ cells in Drosophila.Semantic proximity Read ↗

Induction of female Sex-lethal RNA splicing in male germ cells: implications for Drosophila germline sex determination.Semantic proximity Read ↗

Expression of the Sex-lethal gene is controlled at multiple levels during Drosophila oogenesis.Semantic proximity Read ↗

Primary Sex Determination in Drosophila melanogaster Does Not Rely on the Male-Specific Lethal Complex.Semantic proximity Read ↗

flex, an X-linked female-lethal mutation in Drosophila melanogaster controls the expression of Sex-lethal.Semantic proximity Read ↗

Sex-lethal, master and slave: a hierarchy of germ-line sex determination in Drosophila.Semantic proximity Read ↗

How do germ cells choose their sex? Drosophila as a paradigm.Semantic proximity Read ↗

Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila.Semantic proximity Read ↗

Sex determination in the Drosophila germline is dictated by the sexual identity of the surrounding soma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.