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Article

Sex determination in the germ line of Drosophila melanogaster: activation of the gene Sex-lethal.

Development (Cambridge, England) - 1 Jul 1993

Granadino B, Santamaria P, Sánchez L

Abstract excerpt

The germ line exhibits sexual dimorphism as do the somatic tissues. Cells with the 2X;2A chromosome constitution will follow the oogenic pathway and X;2A cells will develop into sperm. In both somatic and germ-line tissues, the sexual pathway chosen by the cells depends on the gene Sex-lethal (Sx...

Topics

Animals
Basic-Leucine Zipper Transcription Factors
DNA-Binding Proteins
Drosophila Proteins
Drosophila melanogaster
Female
Gene Expression Regulation
Genes, Insect
Germ Cells
Insect Hormones
Male
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nuclear Proteins

RNA-Binding Proteins

Sex Determination Analysis

Transcription Factors

X Chromosome

Source

Identifiers

PMID: 8076519
DOI: 10.1242/dev.118.3.813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8076519-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Sex determination in the germ line of Drosophila melanogaster: activation of the gene Sex-lethal.PMID 8076519Read ↗

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