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Article

A transcriptome-wide association study identifies novel candidate susceptibility genes for prostate cancer risk.

International journal of cancer - 1 Jan 2022

Liu Duo, Zhu Jingjing, Zhou Dan, Nikas Emily G, Mitanis Nikos T, Sun Yanfa, Wu Chong, Mancuso Nicholas, Cox Nancy J, Wang Liang, Freedland Stephen J, Haiman Christopher A, Gamazon Eric R, Nikas Jason B, Wu Lang

Abstract excerpt

A large proportion of heritability for prostate cancer risk remains unknown. Transcriptome-wide association study combined with validation comparing overall levels will help to identify candidate genes potentially playing a role in prostate cancer development. Using data from the Genotype-Tissue Expression Project, we built genetic models to predict normal prostate tissue gene expression using the statistical...

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Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Identifiers

PMID: 34520569
DOI: 10.1002/ijc.33808
PMCID: PMC8595764

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