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Article

FADS2 genotype regulates delta-6 desaturase activity and inflammation in human adipose tissue.

Journal of lipid research - 1 Jan 2016

Vaittinen Maija, Walle Paula, Kuosmanen Emmi, Männistö Ville, Käkelä Pirjo, Ågren Jyrki, Schwab Ursula, Pihlajamäki Jussi

Abstract excerpt

Obesity is associated with disturbed lipid metabolism and low-grade inflammation in tissues. The aim of this study was to investigate the association between FA metabolism and adipose tissue (AT) inflammation in the Kuopio Obesity Surgery study. We investigated the association of surgery-induced weight loss and FA desaturase (FADS)1/2 genotypes with serum and AT FA profile and with AT inflammation, measured as...

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Share to Adipose Tissue
Share to Delta-5 Fatty Acid Desaturase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Fatty Acids, Omega-6

Share to Fatty Acids, Unsaturated

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Source

Open in PubMed Open full text

Identifiers

PMID: 26609056
DOI: 10.1194/jlr.M059113
PMCID: PMC4689336

Genes

FADS1
FADS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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FADS2 genotype regulates delta-6 desaturase activity and inflammation in human adipose tissue.PMID 26609056Read ↗

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